Zirconia Implants for Replacement of a Single Tooth

Inclusion criteria (site level): * partial edentulism (any FDI position between 17 and 47) * healed extraction site (type 2, 3 or 4 implant placement) or native bone * opposing dentition: natural teeth, fixed or removable restoration Exclusion criteria (site level): * inadequate ridge or gap dimensions for the test device (simultaneous bone augmentation allowed) * lack of primary stability of the implant Inclusion criteria (patient level): * self-referred or on purpose referred patient requiring a metal-free, all-ceramic implant therapy * age ≥18 years and ≤ 80 * capable of providing written informed consent and compliance to the protocol * physical status PS1 and PS2 (American Society of Anesthesiologists). Exclusion criteria (patient level): * pregnancy or lactation * inadequate oral hygiene * untreated periodontitis or gingivitis * mucosal diseases such as erosive lichen planus * smoking habit with \>5 cig/d * severe bruxism or clenching habits * uncontrolled diabetes or conditions resulting in or requiring immunosuppression, radiation, chemotherapy, frequent use of antibiotics or antiresorptive medication such as bisphosphonates