The Effect of 3% Diquafosol Ophthalmic Solution on Visual Display Terminal-associated Dry Eye

Inclusion Criteria: * Male or female with a diagnosis dry eye based on Chinese Dry Eye Diagnosis Standard (2020)； * Working in the offices with VDTs more than 4h daily； * Working in the offices with VDTs at least five days per week； * Provision of written informed consent. Exclusion Criteria: * Known allergy to any eye drops * Ocular therapies other than artificial tears * Presence of any of the following conditions: active ocular infection, ocular inflammation, active ocular allergy, contact lens wear, ocular surgical history, laser treatment in the last 3 months, Meibomian gland dysfunction (MGD) over grade 2 (the grade is according to the report of the International Workshop on MGD in 2011), severe blepharitis or obvious inflammation of the eyelid margin, which in the judgment of the investigator may interfere with the interpretation of the study results * Pregnant and lactating women, or those planning a pregnancy over the course of the study * Uncontrolled systemic disease * Hypersensitivity or intolerance to diquafosol(DQS) * Subjects with a history of anxiety and depression