Comparative Abuse Liability Among African American and White Smokers

Inclusion Criteria: * Non-Hispanic African American or white/Caucasian, * ≥21 years old, smoke 5-30 cigarettes per day, * daily cigarette smoker * smoked at current rate for at least 6 months * interested in trying e-cigarettes and heat not burn products * not interested in or unable/unwilling to quit cigarette smoking * willing to complete three in-person study visits * willing to have IV catheter placed Exclusion Criteria: * Interested in quitting cigarettes in the next 30 days * use of smoking cessation pharmacotherapy in the past 30 days * use of non-cigarette tobacco products in the past 30 days * use of e-cigarettes \>5x in lifetime * use of e-cigarettes ≥4 of the past 30 days * use of heat not burn products \>5x in lifetime * use of heat not burn products ≥4 of the past 30 days * weight \< 110 lbs * uncontrolled hypertension (systolic BP ≥ 180 or diastolic BP ≥ 105) * pregnant, plans to become pregnant, or breastfeeding * live \>10 miles from study site (Fairway CRU) * current enrollment is a research study or program that aims to alter tobacco use