The aim of this retrospective study will be to investigate the effect of the preoperative administration of levosimendan on the outcome of patients with compromised cardiac function undergoing cardiac surgery
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
hours of mechanical ventilation
Timeframe: during stay in ICU, approximately 48 hours postoperatively
vasopressor use in operating room
Timeframe: intraoperatively, from induction to end of anesthesia, an average period of 3 hours
vasopressor use in ICU
Timeframe: during stay in ICU, approximately 48 hours postoperatively
inotrope use in operating room
Timeframe: intraoperatively, from induction to end of anesthesia, an average period of 3 hours
inotrope use in ICU
Timeframe: during stay in ICU, approximately 48 hours postoperatively
incidence of arrhythmias
Timeframe: postoperatively, an average period of 7-10 days
incidence of renal dysfunction
Timeframe: postoperatively, an average period of 7-10 days
length of ICU stay
Timeframe: postoperatively, an average period of 7-10 days
hospitalization time
Timeframe: postoperatively, up to 20 days after the operation
incidence of death within the first 30 days after surgery
Timeframe: 30 days after surgery
need of mechanical assist devices intraoperatively
Timeframe: intraoperatively, from induction to end of anesthesia, an average period of 3 hours and postoperatively, an average period of 7-10 days
need of mechanical assist devices postoperatively
Timeframe: postoperatively, an average period of 7-10 days
change from baseline in cardiac output (CO)
Timeframe: 10 minutes after anesthesia induction, 10 minutes after bypass discontinuation, end of operation (an average period of 3 hours after start of surgery), 12 hours after ICU admittance, 24 hours after ICU admittance,
change from baseline in mean arterial pressure (MAP)
Timeframe: 10 minutes after anesthesia induction, 10 minutes after bypass discontinuation, end of operation (an average period of 3 hours after start of surgery), 12 hours after ICU admittance, 24 hours after ICU admittance,
change from baseline in mean pulmonary arterial pressure (MPAP)
Timeframe: 10 minutes after anesthesia induction, 10 minutes after bypass discontinuation, end of operation (an average period of 3 hours after start of surgery), 12 hours after ICU admittance, 24 hours after ICU admittance,
change from baseline in systemic vascular resistance (SVR)
Timeframe: 10 minutes after anesthesia induction, 10 minutes after bypass discontinuation, end of operation (an average period of 3 hours after start of surgery), 12 hours after ICU admittance, 24 hours after ICU admittance,
change from baseline in pulmonary vascular resistance (PVR)
Timeframe: 10 minutes after anesthesia induction, 10 minutes after bypass discontinuation, end of operation (an average period of 3 hours after start of surgery), 12 hours after ICU admittance, 24 hours after ICU admittance,
change from baseline in pulmonary capillary wedge pressure (PCWP)
Timeframe: 10 minutes after anesthesia induction, 10 minutes after bypass discontinuation, end of operation (an average period of 3 hours after start of surgery),12 hours after ICU admittance, 24 hours after ICU admittance,
change from baseline in cardiac function
Timeframe: 10 minutes after anesthesia induction, 10 minutes after bypass discontinuation, end of operation (an average period of 3 hours after start of surgery)