Shigella CVD 31000: Study of Responses With Shigella-ETEC Vaccine Strain CVD 1208S-122

Inclusion Criteria: * Male or female, 18 - 49 years of age * Written informed consent provided * Determined to be in good health\* based on medical history and review of concomitant medications \*Good health as defined by an absence of an active chronic medical condition which requires daily prescription medication(s). Participants may be eligible if the medical condition only requires infrequent as needed (PRN) medication and if the investigator determines that the condition does not pose a risk to participant safety or the assessment of reactogenicity and immunogenicity. Any chronic medical condition which does not require a daily prescription medication but might pose a risk to a participant with rapid dehydration (i.e., rapid intravascular volume changes) would be ineligible to participate. * Documented acceptable results from screening laboratory work (defined in Appendix B), including: * Complete blood count (CBC) with differential for total white blood cell count (WBC), absolute neutrophil count (ANC), hemoglobin (Hg), platelet count * Creatinine, alanine aminotransferase (ALT), total bilirubin * Serum Immunoglobulin A (IgA) level * Human immunodeficiency virus (HIV) antibody, Hepatitis B surface antigen (HBsAg), Hepatitis C virus antibody (HCV) * HLA-B27 histocompatibility testing * Serum Beta human chorionic gonadotropin (β-HCG) test, if the participant is a woman of child-bearing potential * A passing score (≥70%) on a Comprehension Assessment Tool …