Miracle Fruit Powder for the Treatment of Taste Alterations Secondary to Chemotherapy (NCT04629560) | Clinical Trial Compass
CompletedEarly Phase 1
Miracle Fruit Powder for the Treatment of Taste Alterations Secondary to Chemotherapy
48 participantsStarted 2008-08-18
Plain-language summary
Purpose and Objective: Compare the incidence of taste alteration in treatment vs. control arms and Compare weight loss in treatment vs. control arms
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* The inclusion criteria are the following:
* Patients over 18 years old with a life expectancy of 3 months or more.
* Patients with an Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1 or 2
* At enrollment, patients must be able to take oral medications and food reliably without any risk factors for aspiration.
* Patients that have received at least 1 cycle of chemotherapy and have at least 1 more cycle planned.
* Patients receiving the following drug-containing chemotherapy regimens: cyclophosphamide, carboplatin, cisplatinum, gemcitibine, methotrexate, doxorubicin, 5-fluorouracil, paclitaxel, docetaxel, vinorelbine, oxaliplatin, irinotecan and etoposide.
* Patients receiving radiotherapy at the time of chemotherapy are allowed, with the exception of patients receiving radiotherapy for head and neck tumors
* Patients with the ability to understand and the willingness to sign a written informed consent document written in English and answer all appropriate questionnaires in English or Spanish. (see Appendix 3)
* Patients with brain metastases are eligible if neurologically stable after appropriate treatment (surgery and/or radiation).
Exclusion Criteria:
* • Patient that have mechanical obstruction of the alimentary tract.
* Patients who have developed decreased/altered taste sensation for any reason besides chemotherapy
* Patients with malabsorption or intractable vomiting.
* Patients who have extensive denta…
What they're measuring
1
Compare the incidence of taste alteration in treatment vs. control arms