The aim of this study is to investigate the effect of strict blood pressure control versus conventional care in patients with asymptomatic moderate to severe aortic valve stenosis. The study is a randomized (1:1), open label, controlled intervention trial. Hypothesis: 1. Strict BP control for 12 months reduces the progression of LV remodelling compared to conventional treatment. 2. Strict BP control for 2 years reduces the increase in aortic valve calcification and LV remodelling compared to conventional treatment. 3. Strict BP reduction for up to 10 years reduces the need for aortic valve replacement and cardiovascular events compared to conventional care.
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Change in LV mass
Timeframe: Changes will be evaluated after an expected average of 12 months treatment
Change in aortic valve CT calcium volume and aortic peak gradient
Timeframe: Changes will be evaluated after an expected average of 2-3 years treatment
Clinical composite endpoint:
Timeframe: Will be evaluated after an expected average of 7-13 years of treatment