CompletedNot Applicable

Influence of Renal Replacement TherApy on Indirect Calorimetry

Germany100 participantsStarted 2020-10-20

Plain-language summary

Renal replacement therapy may affect carbon dioxide elimination, which may theoretically influence measurement of energy expenditure by means of indirect calorimetry. However, available clinical studies are noct conclusive on this issue. This observational study aims to investigate the effect of renal replacement therapy on indirect calorimetry in critically ill mechanically ventilated patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * simultaneous requirement for mechanical ventilation and renal replacement therapy * informed consent Exclusion Criteria: * age \<18 years * requirement for therapeutic hypothermia * serum lactate \>4 mmol/l * requirement for inspiratory oxygen fraction \>0.6 and positive end-expiratory pressure \>12 mbar * leak in the ventilator circuit (e.g. due to a chest tube) * requirement for extracorporeal circulatory support * refusal to participate in the study.

What they're measuring

energy expenditure

Timeframe: 60 minutes

Trial details

NCT IDNCT04599569

SponsorUniversity of Leipzig

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-05-31

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