Stopped: Unable to recruit participants
This study is examining how a dietary supplement called urea can be used to treat low blood sodium level. Low blood sodium level is a common problem and some studies show that many patients with low blood sodium level suffer from brain fog and/or loss of balance. Unfortunately, it is unknown at this point what the best treatment is for low blood sodium level. With this pilot research study, the investigators are hoping to learn more about whether urea is safe to take, whether patients can tolerate taking urea for several weeks, whether urea increases blood sodium level, and whether urea can help prevent the brain fog and/or loss of balance that some patients with low blood sodium level suffer from. The information obtained with this study is intended to be used to design a larger study in the future to get a definite answer whether urea is beneficial for patients with low blood sodium level.
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Number and Percentage of Participants Who Met Inclusion/Exclusion Criteria and Were Enrolled in the Study
Timeframe: 9 months
Number and Percentage of Participants Enrolled Who Completed the Study
Timeframe: 9 months
Monthly Enrollment Rate
Timeframe: 9 months
Number of Prescribed Urea Doses Taken by Participants
Timeframe: Baseline to day 42 while taking urea
Reasons for Non-Adherence to Urea Therapy
Timeframe: Baseline to day 42 while taking urea
Change in Plasma Sodium Concentration
Timeframe: Baseline to day 42
Change in Percentage Accuracy Action Boundary Selection
Timeframe: Baseline to day 42
Change in Overall Score of Sensorimotor Ability Battery
Timeframe: Baseline to day 42
Change in the Sample Entropy of the Center of Pressure Data From the Force Plate
Timeframe: Baseline to day 42
Change in Percentage Angular Deviation of Vestibular Control System Using Dynamic Representation of Upright Stance
Timeframe: Baseline to day 42
Change in Percentage Angular Deviation of Somatosensory Control System Using Dynamic Representation of Upright Stance
Timeframe: Baseline to day 42
Change in Percentage Angular Deviation of Visual Control System Using Dynamic Representation of Upright Stance
Timeframe: Baseline to 42 days
Change in Percentage Weight Symmetry Using Dynamic Representation of Upright Stance
Timeframe: Baseline to day 42
Change in Movement Latency of Posture Control and Stability Using Dynamic Representation of Upright Stance
Timeframe: Baseline to day 42
Change in Amplitude Scaling of Posture Control and Stability Using Dynamic Representation of Upright Stance
Timeframe: Baseline to day 42
Number and Proportion of Participants Enrolled in the Study With Adverse Events Related to the Use of Urea
Timeframe: Baseline to day 42 while taking urea
Adverse Events Related to Urea
Timeframe: Baseline to day 42 while taking urea