Evaluate the Safety and Effectiveness of Sodium Hyaluronate When Used for the Correction of Nasolabial Folds

Inclusion Criteria: * Age 18 to 65 years of male or female * Wrinkle Severity Rating Scale (WSRS) of bilateral nasolabial folds graded 3 or 4 by blinded evaluator (moderate to severe bilateral nasolabial fold), consistent grade of bilateral nasolabial folds, and the grades approved by the physician who perform the treatment * Agree not to undergo any other under-eye facial surgery (including nose) during the study period Exclusion Criteria: * Injection site with infection or other skin diseases present which may affect the evaluation * With medical history of chromatosis, discoloration, keloid formation, hypertrophic scarring at nasolabial folds * With permanent implants or planning to receive permanent implants during the study period at the injection sites * Hyaluronate facial dermal implant injection or other impermanent dermal fillers injection at injection sites within the past 12 months * With under-eye facial Botox or fat injection within the past 6 months or planning to receive under-eye facial Botox or fat injection during the study period * With under-eye facial chemical or lasers peeling, non-invasive skin tightening, thermocool within the past 3 months or planning to receive these aesthetic procedures during the study period * With prescription medication for nasolabial fold treatment, topical corticosteroid, skinirritating topical products or pigmentation products within the past 2 weeks or planning to take these medication or products during the study period …