The aim is to investigate the impact of prostate and colorectal cancer on mitochondrial quantity and quality along with muscle mass and function and whether this can be modified through the use of a home-based short-term exercise training program. The investigators aim to recruit participants awaiting curative surgery for colorectal and prostate cancer and to assess the variation in baseline mitochondrial activity between them. Participants from both cancer types will then carry out a 4 week home exercise program, this will be randomly allocated to either resistance-based or high-intensity interval training based. Participants will then be re-assessed on the day of their planned surgical procedure to assess the changes effected by the training program. The investigators hypothesize that there will be variation in mitochondrial activity linked to muscle mass across the two cancer types and that home-based exercise programs have the ability to improve mitochondrial activity along with muscle mass.
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Mitochondrial activity across 2 cancer types
Timeframe: Assessed at initial baseline study day across cancer types
Mitochondrial activity change with a short-term home-based exercise program
Timeframe: Assessed over the 4-weeks prior to planned surgical resection
The altered response to training - type between cancer type.
Timeframe: 4-weeks