The purpose of this study is: a) to assess adverse maternal/fetal outcomes in pregnant women randomized to receive the 2- dose Ebola vaccine regimen (Ad26.ZEBOV, MVA-BN-Filo \[Group A\]) and in control women (unvaccinated pregnant women \[Group B\]); and b) to assess adverse neonatal/infant outcomes in neonates/infants born to women randomized to receive the 2-dose Ebola vaccine regimen (Ad26.ZEBOV, MVA-BN-Filo \[Group A\]) and in neonates/infants born to control women (unvaccinated during pregnancy \[Group B\]).
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Percentage of Participants with Maternal Deaths
Timeframe: Up to 6 weeks post-completion/termination of pregnancy
Percentage of Participants with Spontaneous Abortion
Timeframe: Up to 6 weeks post-completion/termination of pregnancy
Percentage of Participants with Stillbirth
Timeframe: Up to 6 weeks post-completion/termination of pregnancy
Percentage of Participants on the Pathways to Preterm Birth
Timeframe: Up to 6 weeks post-completion/termination of pregnancy
Percentage of Participants with Pre-eclampsia/ eclampsia
Timeframe: Up to 6 weeks post-completion/termination of pregnancy
Percentage of Participants with Antenatal Bleeding
Timeframe: Up to 6 weeks post-completion/termination of pregnancy
Percentage of Participants with Postpartum Hemorrhage
Timeframe: Up to 6 weeks post-completion/termination of pregnancy
Percentage of Newborns with Major Congenital Malformations born to Participants
Timeframe: At birth
Percentage of Newborns Small for Gestational age (SGA) born to Participants
Timeframe: At birth
Percentage of Newborns with Low Birth Weight born to Participants
Timeframe: At birth
Percentage of Newborns with Preterm Birth born to Participants
Timeframe: At birth
Percentage of Neonatal Deaths in Neonates Born to Participants
Timeframe: Up to 28 days
Percentage of Infants (of Participants) who Fail to Thrive
Timeframe: From birth up to 14 weeks of age