CompletedNot Applicable

Immunological Response After Shrimp Oral Immunotherapy Treatment

Thailand20 participantsStarted 2020-08-28

Plain-language summary

Oral immunotherapy is effective in desensitized food allergy. Shrimp allergy is increasing in Thailand. So the purpose of our study is to determine level of specific immunoglobulin E antibodies to shrimp, Immunoglobulin G4 and immunoblot analysis in shrimp allergy patients after shrimp oral immunotherapy.

Who can participate

Age range12 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 12 - 40 years old * History of Immunoglobulin E-mediated shrimp allergy \> 3 episode/year or disturb quality of life * Positive oral food challenge test for shrimp Exclusion Criteria: * History of shrimp anaphylaxis (include cardiovascular or neurological symptoms) * Shellfish dependent exercise induced anaphylaxis * History of cardiovascular disease, uncontrolled asthma, severe atopic dermatitis * History of Beta-blocker, Angiotensin-converting enzyme inhibitor, Angiotensin receptor blocker, Calcium channel blocker

What they're measuring

Change in Eliciting Dose of Shrimp During Oral Food Challenge

Timeframe: Baseline and 12 months

Trial details

NCT IDNCT04552522

SponsorMahidol University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-31

Results submitted2026-01-18

View on ClinicalTrials.gov More Allergy to Shrimp trials