Importance of the Microtubule Cytoskeleton in Oocyte Competence (NCT04546412) | Clinical Trial Compass
CompletedNot Applicable
Importance of the Microtubule Cytoskeleton in Oocyte Competence
Portugal6 participantsStarted 2020-10-09
Plain-language summary
This study will assess if there are microtubule cytoplasmic features specifically associated with oocyte vitrification.
Who can participate
Age range18 Years – 34 Years
SexFEMALE
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Inclusion Criteria:
* Informed consent form dated and signed.
* Already consented to perform oocyte donation.
* Age ≥18 and \<35 years old.
* AFC ≥20.
* BMI ≥18.5 Kg/m2 and \<30 Kg/m2.
* Two ovaries present.
* No current pregnancy-wish.
Exclusion Criteria:
* Simultaneous participation in another clinical study or participation in another clinical study before inclusion in the present study that could affect its objectives.
* Previous history of poor ovarian response (\<4 oocytes retrieved) with a maximal dose of ovarian stimulation (≥300 IU/day).
* Use of hormone contraceptives in the month preceding eventual inclusion.
* Presence of a medical condition which is known to affect ART outcome (e.g. thyroid dysfunction).
* Active female smoking.
* Ongoing pregnancy.
* Current use of anti-depressants, anti-psychotics, steroids, antiepileptics or chemotherapy.
* Known allergy or hypersensitivity to any of the study non-IMP.
What they're measuring
1
Ocurrence of diferent features in the microtubule cytoskeleton
Timeframe: From October 2020 up to December 2020
Trial details
NCT IDNCT04546412
SponsorInstituto Valenciano de Infertilidade de Lisboa