CompletedNot Applicable

Importance of the Microtubule Cytoskeleton in Oocyte Competence

Portugal6 participantsStarted 2020-10-09

Plain-language summary

This study will assess if there are microtubule cytoplasmic features specifically associated with oocyte vitrification.

Who can participate

Age range

18 Years – 34 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Informed consent form dated and signed. * Already consented to perform oocyte donation. * Age ≥18 and \<35 years old. * AFC ≥20. * BMI ≥18.5 Kg/m2 and \<30 Kg/m2. * Two ovaries present. * No current pregnancy-wish. Exclusion Criteria: * Simultaneous participation in another clinical study or participation in another clinical study before inclusion in the present study that could affect its objectives. * Previous history of poor ovarian response (\<4 oocytes retrieved) with a maximal dose of ovarian stimulation (≥300 IU/day). * Use of hormone contraceptives in the month preceding eventual inclusion. * Presence of a medical condition which is known to affect ART outcome (e.g. thyroid dysfunction). * Active female smoking. * Ongoing pregnancy. * Current use of anti-depressants, anti-psychotics, steroids, antiepileptics or chemotherapy. * Known allergy or hypersensitivity to any of the study non-IMP.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Ocurrence of diferent features in the microtubule cytoskeleton

Timeframe: From October 2020 up to December 2020

Trial details

NCT IDNCT04546412

SponsorInstituto Valenciano de Infertilidade de Lisboa

Sponsor typeNETWORK

Study typeOBSERVATIONAL

Primary completion2021-10-12

View on ClinicalTrials.gov More ART trials