Adacel® Booster Vaccination for CMI Assay Development

Inclusion Criteria: * Age ≥16years * Primed during infancy with an acellular pertussis vaccine * Good general health status, as determined by history no greater than 30 days prior to administration of the first test article * Written informed consent provided * If female of child-bearing potential, has a negative pregnancy test on the day of consent and has agreed to continue adequate contraception until after the last blood draw. Exclusion Criteria: * Not primed in infancy with an acellular pertussis vaccine * History of anemia * Underlying chronic medical condition requiring ongoing monitoring by a physician (e.g., diabetes, seizure disorder) * Underlying cardiac and/or pulmonary disease including hypertension, angina, prior myocardial infection, asthma, emphysema, chronic bronchitis, and pulmonary tuberculosis * Pregnant (known before or established at the time of screening using a urine-based test) * Immunocompromised (reporting HIV/AIDS positive or receiving immunosuppressive therapy involving steroids) * Vaccinated against pertussis within previous 5 years * Refusing to get an Adacel® (TdaP) vaccination dose