CompletedEarly Phase 1

Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery

United States124 participantsStarted 2020-10-08

Plain-language summary

Bleeding after Mohs micrographic surgery for skin cancer is a low risk complication that can occur. This study aims to determine the effect of a drug, often used to reduce bleeding, called tranexamic acid when applied topically to the skin wound after surgery.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All adult (18 years or older) patients presenting for Mohs micrographic surgery (MMS) for the treatment of melanoma or nonmelanoma skin cancer (NMSC) with a wound that will be healing by granulation Exclusion Criteria: * Patients must not be pregnant or breastfeeding. * Patients must not have a known allergic reaction or sensitivity to TXA * Patient must not have an international normalized ratio (INR) out of therapeutic range if on warfarin.

What they're measuring

Frequency of Postoperative Hemorrhagic Complications

Timeframe: three days

Rate of Clinic Evaluations of Postoperative Hemorrhagic Complications

Timeframe: three days

Rate of Treatment Interventions for Postoperative Hemorrhagic Complications

Timeframe: three days

Trial details

NCT IDNCT04541303

SponsorUniversity of Missouri-Columbia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-30

Results submitted2023-05-16

View on ClinicalTrials.gov More Postoperative Wound Haemorrhage trials