The primary objective of the study is to evaluate the long-term safety and tolerability of subcutaneous fremanezumab in the preventive treatment of migraine in pediatric participants 6 to 17 years of age (inclusive at enrollment in the pivotal study). Secondary objectives are to evaluate the efficacy of subcutaneous fremanezumab in pediatric participants with migraine and to evaluate the immunogenicity of fremanezumab and the impact of ADAs on clinical outcomes in pediatric participants exposed to fremanezumab. The total duration of the study is planned to be up to 84 months.
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Incidence of adverse events
Timeframe: Day 1 - Day 393
Incidence of participants with clinically significant changes in laboratory values
Timeframe: Day 1 - Day 253
Incidence of abnormal standard 12-lead electrocardiogram (ECG) findings
Timeframe: Day 1 - Day 253
Incidence of abnormal vital signs
Timeframe: Day 1 - Day 253
Incidence of abnormal physical examination findings
Timeframe: Day 1- Day 393
Yes/No suicidality ideation
Timeframe: Day 1 - Day 393