The primary objectives of this study are to evaluate the tolerability and reactogenicity of a single injection of up to 5 dose levels of mRNA-1345 in younger adults, women of child-bearing potential, and older adults including Japanese older adults; of 3 injections of the middle dose level of mRNA-1345 given 56 days apart in younger adults; of a booster injection of mRNA-1345 given approximately 12 and 24 months after the primary injection in older adults; and of 3 injections of 1 of 2 dose levels of mRNA-1345 given 56 days apart in children who are RSV-seropositive.
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Number of Participants with Solicited Local and Systemic Adverse Reactions (ARs)
Timeframe: Up to Day 737 (7 days after each injection)
Number of Participants with Unsolicited Adverse Events (AEs)
Timeframe: Up to Day 758 (28 days after the last injection)
Number of Participants with Serious AEs or Medically Attended AEs (MAAEs)
Timeframe: Up to Day 1095 (End of Study)