The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Co… (NCT04514354) | Clinical Trial Compass
CompletedNot Applicable
The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Conditions
United States21 participantsStarted 2015-04
Plain-language summary
Sudden cardiac death (SCD) is the number one cause of on-duty firefighter death. It is most likely to occur in adults who are not physically fit that engage in sudden vigorous exercise. Cardiorespiratory physical fitness (also known as aerobic fitness) is a major heart disease risk factor. In FIT and FIRED UP, the study investigators looked at the influence of cardiorespiratory fitness on blood pressure, heart rate, and other heart markers taken from the blood before and after a vigorous exercise test to maximal effort among firefighters from a local fire department in Connecticut. In addition, the investigators also looked at how lifestyle habits including physical activity, nutrition, stress, and sleep may influence our findings. It was hypothesized that aerobically fit firefighters would show less stress on their heart than unfit firefighters.
Who can participate
Age range
21 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Subjects had to be full active duty firefighters employed by the local fire department in central Connecticut (CT).
* Subjects confirmed that they were taking the same medication for four weeks prior to Visit 1 and continued taking that medication throughout the duration of the study.
Exclusion Criteria:
* Subjects were excluded from the study if they were not able to comply with all study procedures as described in Visit 1, or in the event of injury or illness that would not enable them to participate.
* If subjects had resting blood pressure readings that were \> 160 for systolic blood pressure and/or ≥ 100 mmHg for diastolic blood pressure, they were excluded from the study and referred to their primary care physician for follow up.
* Subjects that were excluded from the study were not penalized in any way by the researchers or the administrators of the local fire department.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Ambulatory Blood Pressure (ABP)
Timeframe: ABP was measured at the conclusion of Visits 3 and 4 during weeks 3 and 4.
2
Change in Resting Blood Pressure
Timeframe: Resting BP was measured during Visits 3 and 4 during weeks 3 and 4.
3
Change in Fasted Blood Sampling
Timeframe: The blood sampling occurred at Visit 3 or 4 during the GEST Visit during week 3 or 4.
4
Change in Fasted Blood Sampling
Timeframe: The blood sampling occurred at Visit 3 or 4 during the GEST Visit during week 3 or 4.
5
Change in Fasted Blood Sampling
Timeframe: The blood sampling occurred at Visit 3 or 4 during the GEST Visit during week 3 or 4.
6
Dietary Intake
Timeframe: The questionnaire was filled out during Visit 3 or 4 at the Control Visit during week 3 or 4.