The objective of the study is to test the capacity of a 12-weeks Turmipure GOLD® supplementation to reduce joint discomfort.
Who can participate
Age range35 Years – 80 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Consent to the study and to comply with study product
* Who have a BMI between 18 and 32 kg/m²
* Who has mild to moderate knee pain for at least 3 months before enrollment (VAS between 40 to 70 on 100mm scale after respecting a washout period depending on the half-life of the excluded medications)
* Who has radiographic evidence of Kellgren-Lawrence score 0, 1, 2 and 3 in the tibio-femoral compartment of the target knee
* Who is able to perform the physical performance-based tests and understands all questions from the WOMAC questionnaire
* Who is willing to refrain from taking any pain reliever (OTC or prescription) and other pharmacological, nutritional agent (e.g. glucosamine), device or therapy (e.g. acupuncture) which may influence the study outcome during the entire trial (other than determined authorized rescue medication)
* Who is willing to not change dietary habits, level of physical activity (including any heavy physical work with high loading of the knee joints) and body weight
Exclusion Criteria:
* Subjects with any clinically significant levels of the safety parameters at screening
* Pregnant or lactating females, or wishing to become pregnant during the study
* Subject with joint pain related to some predisposing conditions that have adversely altered the joint tissues often due to a specific cause
* Subject with Kellgren-Lawrence grade 4 in the tibio-femoral compartment of the target knee
* Who has clinically apparent tense effusion of…