Comparison Trial of Open-tip Pulsed Needle Biopsy and Conventional Core Biopsy in Axillary Lymph Nodes

Inclusion Criteria: * Women in screening and symptomatic clinics aged 18 years or older with breast masses scored as 1 of the following: * M3, M4 or M5 (mammographically uncertain, suspicious or highly suspicious of malignancy) * MRI5 (highly suspicious of malignancy on MRI) * U3, U4 or U5 (ultrasonically uncertain, suspicious or highly suspicious of malignancy) * have histologically proven breast cancer * who have ipsilateral axillary lymph nodes which are described as indeterminate or suspicious for metastatic disease and indicated for biopsy, as determined by individual breast unit criteria * are able to give informed consent for the study Exclusion Criteria: * Previous ipsilateral axillary surgery * Target lymph node not suitable for needle biopsy due to its close proximity to critical structures such as major blood vessels * Unable to give written informed consent in English