CompletedNot Applicable

Asymptomatic Renal Calculi in Recurrent Urinary Tract Infections

United States94 participantsStarted 2020-09-09

Plain-language summary

This study will assess patients who have recurrent urinary tract infections and kidney stones which are not blocking the kidney or causing other problems. Currently, we don't know if taking out these stones will improve recurrent urinary tract infections or not. Patients will make a decision with their surgeon about removing or monitoring their stone(s). Whether or not their infections continue with surgery or monitoring will be noted, and this information may help to inform future treatment decisions. The purpose of this study is to assess if treatment of these asymptomatic stones affects the rate of recurrent urinary tract infections.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria (all of the following): * recurrent UTIs, defined as 3 positive urine cultures of specific organisms with symptoms within 12 months (or 2 positive cultures with symptoms within 6 months) prior to clinical assessment * non-obstructing renal stone(s) on imaging within 6 months of initial visit Exclusion Criteria: * age \< 18 years * pregnancy * hydronephrosis or evidence of obstruction * presence of a foreign body in urinary tract (e.g. Foley, ureteral stent, nephrostomy tube) at the time of UTI diagnosis * concurrent bladder calculi * Urinary diversion or previous surgery involving segments of bowel interposed into the urinary tract (ileal conduit, ileal ureter etc.)

What they're measuring

Recurrent urinary tract infections

Timeframe: 12 months

Trial details

NCT IDNCT04495699

SponsorVanderbilt University Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-09-01

View on ClinicalTrials.gov More Urinary Tract Infections trials