CompletedNot Applicable

Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial

Ethiopia, South Africa183 participantsStarted 2021-06-04

Plain-language summary

This qualitative study is designed to elicit the perspectives of relevant stakeholders to adapt a community-based TB/HIV intervention aimed on providing home-based TB prevention treatment (TPT) initiation for child TB contacts, to design its implementation strategy and, post intervention, to assess lessons learned for future scale up. Participants will include policy makers and health system managers, nurse and physician providers, community health team members, and child caregivers of TB-exposed children. Stakeholders will be asked to participate in two interviews, one prior to the cluster randomized trial assessing this intervention and one after the cluster randomized trial. Trained interviewers will conduct 1-hour semi-structured in-depth interviews that will be audio-recorded, translated and transcribed for thematic analysis using a priori and emergent domains of interest. Free-listing, ranking exercises and cultural consensus will be used to identify context-specific intervention adaptations and implementation strategies.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria for Interview 1: * Adult caregiver (18 years of age or older) of a child (\<15 years of age) who was exposed to TB in the last two years where at least one child was evaluated for and offered either TB preventive therapy or TB treatment. or * Community health team members from one of the Ethiopian or South African clinics in which the CHIP-TB trial will be conducted. or * TB nurse from one of the 16 Ethiopian or South African clinics in which the study will be conducted or * Pediatrician or medical officer working in pediatrics at the relevant Ethiopian or South African District Hospital who sees outpatient pediatric consultations including TB-exposed children or * Program manager or policy maker in the relevant Ethiopian or South African district or provincial office who manages TB, PMTCT, and/or other pediatric programming Exclusion Criteria for Interview 1: * Any adult caregivers, community health team members, TB nurses, medical officers or pediatricians, program managers or policy makers who are unable or unwilling to provide informed consent for both the interview and audio-recording Inclusion Criteria for Interview 2: * Any community health team members, TB nurses, medical officers or pediatricians, program managers or policy makers who participated in the program for at least 3 months * Any adult caregiver whose child participated in the community-based TB prevention program Exclusion Criteria for Interview 2: * Any adult caregivers, …

What they're measuring

Perception of intervention adaptations as assessed by an in-depth interview

Timeframe: Within six months prior to CHIP-TB trial initiation

Perception of implementation strategies as assessed by an in-depth interview

Timeframe: Within six months prior to CHIP-TB trial initiation

Perception of the social context of the community-based health teams as assessed by an in-depth interview

Timeframe: Within six months prior to CHIP-TB trial initiation

Perception of the lessons learned as assessed by an in-depth interview

Timeframe: Within four months after CHIP-TB Trial completion

Trial details

NCT IDNCT04494516

SponsorJohns Hopkins University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06-30

View on ClinicalTrials.gov More Tuberculosis Infection trials