RecruitingNot Applicable

CARbon monoxidE intoxiCatiOn in Korea: Prospective Cohort (CARE CO Cohort)

South Korea1,500 participantsStarted 2020-07-29

Plain-language summary

This prospective cohort study enrolls subjects who experience carbon monoxide (CO) poisoning. The purpose of the study is to evaluate therapeutic effects of various treatments and short and long-term outcomes in CO poisoned patients. In addition, complications of brain and heart susceptible to CO are investigated through various ways and the association between complications and the patient's prognosis is also investigated. All subjects will be regularly monitored by physicians participating in this study.

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Acute CO poisoning Exclusion Criteria: * Declined to enrollment in the study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Therapeutic response to HBO at 1 month

Timeframe: At 1 month after CO exposure

Therapeutic response to HBO at 6 months

Timeframe: At 6 months after CO exposure

Predictors and model development for participants with poor outcome including mortality, and neurocognitive and psychological sequelae at 1 month after CO exposure evaluated by such as neurocognitive function tests

Timeframe: Within 1 month after CO exposure

Predictors and model development for participants with poor outcome including mortality, and neurocognitive and psychological sequelae at 6 months after CO exposure evaluated by such as neurocognitive function tests

Timeframe: Within 1 month after CO exposure

Predictors and model development for participants with poor outcome including mortality, and neurocognitive and psychological sequelae at 12 months after CO exposure evaluated by such as neurocognitive function tests

Timeframe: Within 1 month after CO exposure

Trial details

NCT IDNCT04490317

SponsorWonju Severance Christian Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2030-12

Contact for this trial

Yong Sung Cha, MD

+82-33-741-1615 emyscha@yonsei.ac.kr

View on ClinicalTrials.gov More Carbon Monoxide Poisoning trials

Plain-language summary

What they're measuring

Therapeutic response to HBO at 1 month

Timeframe: At 1 month after CO exposure

Therapeutic response to HBO at 6 months

Timeframe: At 6 months after CO exposure

Timeframe: Within 1 month after CO exposure