Safety of a Sheath Cryoprobe Bronchoscopic Transbronchial Biopsy Technique

Inclusion Criteria: * Male or Female, ≥ 18-years-old * Scheduled to undergo bronchoscopy with transbronchial biopsy as the standard medical care determined by their treating pulmonologist Exclusion Criteria: * Pregnant or nursing females, or females of child bearing potential who refuse to take a pregnancy test prior to enrollment * Individuals with current or recent systematic conditions, such as uncontrolled hypertension (systolic \> 200 mmHg or diastolic \> 110 mmHg), type 1 diabetes, severe pulmonary hypertension, acute kidney injury, stroke (within the last 6 months) or myocardial infarction (within the last 3 months) * Presence of bleeding disorder * Platelet count \<50,000 * Current use of systemic anticoagulation or antiplatelet therapy without the ability to hold therapy for the recommended amount of time prior to an invasive procedure (aspirin monotherapy is acceptable) * International Normalized Ratio (INR) \<1.5 * Robotic Bronchoscopy