Efficacy, Tolerance and Safety of Split Dose Bowel Preparation for Colonoscopy: 4L Polyethylene G… (NCT04474002) | Clinical Trial Compass
CompletedPhase 4
Efficacy, Tolerance and Safety of Split Dose Bowel Preparation for Colonoscopy: 4L Polyethylene Glycol (PEG) Versus 1L Polyethylene Glycol Plus Sodium Picosulfate-magnesium Citrate (SPMC)
Hong Kong158 participantsStarted 2020-12-07
Plain-language summary
4L split dose PEG is the gold standard for bowel preparation, however it comes with poor tolerability and poor compliance. Combination of PEG with different agent is useful in reducing total volume, improving compliance and tolerance of patient.
The objective of this study is to demonstrate that combination bowel preparation, PEG plus SPMC solution, has similar efficacy and safety profile whereas with a better tolerance when compared to large volume PEG.
Who can participate
Age range18 Years – 65 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Patient who mentally capable to consent for participating the trial
✓. 18 - 65 years old
✓. Scheduled for 1st colonoscopy
✓. Elective outpatient colonoscopy
Exclusion criteria
✕. Prior colorectal or abdominal-pelvic surgery
✕. Inflammatory bowel disease
✕. Active bowel condition eg intestinal obstruction
✕. Gastrointestinal disorders eg active ulcer, gastric outlet obstruction, gastroparesis and hypomotility syndrome