Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain
Stopped: No Insurance Coverage
United States0Started 2025-01-15
Plain-language summary
The objective of this investigation is to evaluate the safety of the geniculate artery embolization (GAE) procedure with HydroPearl® Microspheres in 30 patients with knee pain caused by osteoarthritis with 24 months follow-up. The GAE procedure is an arterial embolization procedure that blocks abnormal blood vessels caused be knee arthritis in order to evaluate the effect on knee pain.
Who can participate
Age range40 Years
SexALL
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Inclusion criteria
✓. Provide informed consent
✓. Age ≥ 40 years
✓. Moderate to severe knee pain (VAS \>40 mm)
✓. Pain refractory to 3 months of conservative treatments, including at least one of the following:
✓. Kellgren-Lawrence radiographic grade 1, 2, or 3 disease
✓. MRI features of active synovitis (synovial thickening and/or enhancement on MRI).
✓. Ineligibility or refusal of surgical management.
✓. Local knee tenderness
Exclusion criteria
✕. Rheumatoid or infectious arthritis
✕. Advanced lower extremity atherosclerosis that would limit selective angiography
✕. Local knee infection
✕. Prior knee surgery (excluding arthroscopic/meniscal interventions)