Lifestyle Intervention for Patients With Impaired Glucose Regulation (NCT04469400) | Clinical Trial Compass
CompletedNot Applicable
Lifestyle Intervention for Patients With Impaired Glucose Regulation
China116 participantsStarted 2020-05-01
Plain-language summary
Impaired glucose regulation (IGR) is closely related to overweight/obesity. By studying different dietary patterns (energy-limited diet vs. low-carbohydrate diet) and intensive lifestyle interventions combined with blood glucose monitoring, glucose regulation of overweight/obesity is affected. To improve the blood glucose and related metabolic indexes of patients with impaired (IGR), establish 1-2 clinical intervention programs for impaired glucose regulation.
Who can participate
Age range18 Years – 65 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18-65 years old ② Fasting blood glucose is between 5.6-6.9 mmol/L (100-125mg/dL) or oral glucose tolerance test (OGTT) 2h plasma glucose (2h-PG) is 7.8-11.1 mmol/L (140-200 mg/dL)
* 24 kg/m2 ≤ BMI ≤ 35 kg/m2
* Those who are willing to accept assessment and sign informed consent.
Exclusion Criteria:
* Patients diagnosed with diabetes or undergoing diabetes treatment;
* Receiving drugs or surgery for weight loss at present or in the past 3 months;
* Receiving corticosteroid or thyroid hormone treatment;
* Secondary obesity caused by endocrine, genetic, metabolic and central nervous system diseases;
* Patients with abnormal liver function (alanine aminotransferase or/and aspartate aminotransferase exceeding the upper limit of normal value 3 times); patients with abnormal renal function (serum creatinine exceeding the upper limit of normal value); suffering from kidney disease and other diseases that need to control protein intake;
* Diseases affecting the digestion and absorption of food (such as chronic diarrhea, constipation, severe gastrointestinal inflammation, active gastrointestinal ulcer, gastrointestinal resection, cholecystitis/cholecystectomy, etc.); ⑦ Suffering from cardiovascular and cerebrovascular diseases, grade 3 hypertension, chronic hepatitis, malignant tumors, anemia, mental illness and memory disorders, epilepsy and other diseases; ⑧ Suffering from infectious diseases such as active tuber…
What they're measuring
1
Fasting blood glucose
Timeframe: ten weeks
2
Blood glucose 2 hours after meal
Timeframe: ten weeks
Trial details
NCT IDNCT04469400
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University