Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection

Healthy Volunteers: Inclusion Criteria: * Male or female age 18 - 55 * Weight 40-125 kg Exclusion Criteria: * Any clinically significant chronic or acute medical condition that makes the volunteer unsuitable for participation * History or evidence of drug or alcohol abuse * History of allergic reactions to monoclonal antibodies or antibody fragments * History of anaphylaxis CHB Patients: Inclusion Criteria: * Male or female age 18 - 65 * Weight 40-125 kg * Chronic HBV infection for \>/= 6 months Exclusion Criteria: * Any clinically significant chronic or acute medical condition that makes the participant unsuitable for participation * Significant fibrosis or cirrhosis * History or evidence of drug or alcohol abuse * History of chronic liver disease from any cause other than chronic HBV infection * History of hepatic decompensation * History of anaphylaxis * History of allergic reactions to monoclonal antibodies or antibody fragments * History of immune complex disease * Active infection with HIV, HCV or hepatitis Delta virus