Hydrolyzed Fish Cartilage Effect on Knee Joint Functionality and Discomfort in Adult Population (NCT04420091) | Clinical Trial Compass
CompletedNot Applicable
Hydrolyzed Fish Cartilage Effect on Knee Joint Functionality and Discomfort in Adult Population
Belgium32 participantsStarted 2020-06-11
Plain-language summary
This study is an exploratory, non-comparative, multi-centric trial in 30 free-living healthy male and female subjects with moderate knee joint discomfort and loss of functionality.
The objective of this trial is to determine whether oral administration of Cartidyss, a concentrated fish cartilage extract, can contribute to the improvement of knee joint functionality and discomfort in adult population
Who can participate
Age range
40 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or female
* Age limits (see above)
* Body Mass Index BMI ≤ 35 kg/m2
* Knee discomfort score at rest over the last 24 hours on the most painful knee evaluated on VAS (0-100) ≥ 40 at baseline
* Able to follow the instructions of the study
* Having signed an informed consent
Exclusion Criteria:
* related to knee:
* Recent trauma (\< 1 month) of the knee responsible of the symptomatic knee;
* Concurrent articular disease interfering with the evaluation of knee pain left to the Investigator's discretion
* Prosthesis in the target knee
* related to treatments:
* Analgesics to manage knee pain 24 hours before inclusion visit;
* Corticosteroids injection in the target knee in the last month;
* Hyaluronan injection in the target knee in the last 6 months;
* Arthroscopy in the last 6 months
* Oral corticotherapy ≥ 5mg/day (in Prednisolone equivalent) in the last 3 months;
* Symptomatic slow-acting drugs for osteoarthritis (SYSADOA) or dietary supplement, i.e., curcuma extract, chondroitin, glucosamine, diacerein or avocado-soya unsaponifiables int he last 3 months
* Contraindications to Cartidyss: hypersensitivity or allergy to the product components (fish)
* Treatments based on strontium ranelate, bisphosphonates, selective estrogen-receptor modulator (SERM) and parathormone (PTH) in the last 12 months
* related to associated diseases :
* Any severe, uncontrolled and limiting diseases left to the Investigator's discretion
* An…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Evaluate the effect of Cartidyss on knee functionality and discomfort after 3 months of supplementation