Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning a… (NCT04419831) | Clinical Trial Compass
CompletedNot Applicable
Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning and Executive Function
United States81 participantsStarted 2022-04-14
Plain-language summary
The study design is to assess the between groups factor (controls, chronic pain, addicted individuals) and repeated measures factor of pain/stress (pain vs no pain) along with a longitudinal component to assess stress, pain and addictive behaviors in daily life.
Who can participate
Age range18 Years – 50 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Between ages 18-50 years;
✓. Able to read and write English;
✓. 50 individuals meeting DSM V criteria for Binge Heavy drinkers, using NIAAA criteria for alcohol intake 50 individuals meeting DSM V criteria for Cannabis Use Disorder 50 individuals meeting DSM V criteria for Alcohol Use Disorder 50 Individuals with Moderate to Severe Pain 50 individuals meeting DSM V criteria for Opioid Use Disorder who are initiating treatment
✓. Physically healthy as determined by Physical Exam, EKG and blood analyses
✓. Body Mass Index (BMI) in the 18-30 range;
Exclusion criteria
✕. Any psychotic disorder or current psychiatric symptoms requiring specific attention, including active symptoms of psychosis or suicidal/homicidal ideation.
✕. Any Current Substance Use Disorder including alcohol, cannabis, cocaine, opioids, sedatives/hypnotics. For alcohol, cannabis, and opioid subjects, exclusion for the abused drug will not apply.
✕. Individuals taking any prescription medications or over-the counter medications regularly;
✕. Women with irregular menstrual cycles or who are nursing, dysmennorheic, amenorrheic, menopausal, or had premenstrual dysphoric disorder or those on birth control pills;
✕. Women who are pregnant as determined by the urine pregnancy test at each laboratory admission;