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Comparative Evaluation of Two PRF Formulations on Quality of Life and Healing of Apicomarginal Defects

India32 participantsStarted 2019-12-11

Plain-language summary

Healing of apicomarginal defects using 2 different formulations of PRF i.e PRF -high and PRF-medium will be assessed and compared using 2D and 3D criteria. Also, in vitro evaluation of the PRF formulations and quality of life will be compared between the two groups.

Who can participate

Age range16 Years – 60 Years

SexALL

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Inclusion criteria

✓. Patients of age 16 years and above.
✓. Patients with no general medical contraindications for oral surgical procedures (ASA-I and ASA-II according to the classification of the American Society of Anesthesiologist's.
✓. periapical defect with periodontal communication.
✓. Periodontal pocket \>6mm with apicomarginal communication confined to buccal aspect of interproximal space or mid buccal aspect of the root.
✓. Negative response to vitality test.
✓. failed previous root canal treatment with purulent discharge or failed previous surgery or recurrent episode of purulent discharge.

Exclusion criteria

✕. Presence of buccal bone on flap elevation.
✕. Unrestorable tooth.
✕. fractured /perforated roots.
✕. smokers.
✕. pregnant females and lactating mothers

What they're measuring

Healing of apicomarginal defects.

Timeframe: Baseline to 12 months

Trial details

NCT IDNCT04396743

SponsorPostgraduate Institute of Dental Sciences Rohtak

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-04-11

View on ClinicalTrials.gov More Apico Marginal Defects trials