UnknownNot Applicable

Fractional Microneedling RF vs Intralesional Steroid With & Without Microneedling in Hypertrophic Scars

Egypt30 participantsStarted 2020-05-10

Plain-language summary

Comparing between the effect of Fractional Microneedling Radiofrequency Versus Intralesional Steroid Injection with and without Microneedling on Tissue levels of PDGF \& CTGF in Hypertrophic Scars

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with mature hypertrophic scars. * Patients with age above 18 years. * Both males and females. * Patients with two separate lesions, each 3 cm length at least OR a large sized lesion 10 cm length at least. Exclusion Criteria: * Patients with unrealistic expectations. * Patients with active skin infections or autoimmune diseases. * Non-compliant patients. * Patients who had received any form of treatment for scars during the last six months. * Recent use of isotretinoin within six months prior to the procedures. * Patient with known allergy to lidocaine. * Pregnancy \& Lactation.

What they're measuring

Calculation of patient and observer scar assessment scale (POSAS) to assess change of hyertrophic scars

Timeframe: 6 months

Photographic documentation will be performed to assess change of hypertrophic scar(s)

Timeframe: 6 months

Measurement of tissue levels of both platelet derived growth factor (PDGF) & connective tissue growth factor (CTGF) to assess change of hypertrophic scars

Timeframe: 6 months

Trial details

NCT IDNCT04389619

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-12

View on ClinicalTrials.gov More Hypertrophic Scars trials