A Cone Beam Computed Tomographic Evaluation of Healing of Apicomarginal Defects Using Autologous Platelet Aggregates

Inclusion Criteria: * A negative response to vitality tests with radiographic evidence of periapical radiolucency with no general medical contraindications for oral surgical procedures. * Apicomarginal communication having probing depth \> 6mm. * Patients with no general medical contraindications for oral surgical procedures. * Recurrent episodes of purulent discharge. * Failed previous root canal treatment. * Failed previous surgery with persistent bony lesion. * Adequate final restoration with no clinical evidence of coronal leakage. Exclusion Criteria: * Clinical or radiographic evidence of root fracture. * Resorptive processes involving more than apical third of the root. * Any systemic disease contraindicating oral surgery including uncontrolled diabetes and pregnancy. * Any condition effecting rate of healing like smoking.