This is a single-group, open-label, multi-site study in pediatric participants with human immunodeficiency virus type 1 (HIV-1) infection, aged 4 weeks to \<12 years and weighing \<45 kg, who are treatment-naive (TN) or have been virologically suppressed (VS) on stable combination antiretroviral therapy (cART) for ≥3 months with no history of treatment failure. The primary objectives are: * To evaluate the steady state pharmacokinetics (PK) of doravirine (DOR) \[MK-1439\] when given in combination with 2 nucleoside/nucleotide analog reverse transcriptase inhibitors (NRTIs) or as part of the fixed-dose combination (FDC) of DOR/lamivudine (3TC)/tenofovir disproxil fumarate (TDF) in participants ≥6 to \<12 years and weighing ≥14 to \<45 kg. * To evaluate the safety and tolerability of DOR when given with 2 NRTIs or as part of the FDC of DOR/3TC/TDF, in participants ≥6 to 12 years and weighing ≥14 to \<45 kg, through Week 24.
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Area Under the Concentration-Time Curve (AUC) From 0 to 24 Hours Postdose (AUC0-24hr) of Doravirine (DOR) Following Once-Daily Dosing in Plasma at Steady-State
Timeframe: Intensive pharmacokinetic sampling: at designated timepoints up to 24 hours postdose
Maximum Concentration (Cmax) of DOR Following Once-Daily Dosing in Plasma at Steady-State
Timeframe: Intensive pharmacokinetic sampling: at designated timepoints up to 24 hours postdose
Concentration at 24 Hours (C24) of DOR Following Once-Daily Dosing in Plasma at Steady-State
Timeframe: Intensive pharmacokinetic sampling: at designated timepoints up to 24 hours postdose
Time to Maximum Concentration (Tmax) of DOR Following Once-Daily Dosing in Plasma at Steady-State
Timeframe: Intensive pharmacokinetic sampling: at designated timepoints up to 24 hours postdose
AUC From 0 to 12 Hours Postdose (AUC0-12hr) of DOR Following Twice-Daily Dosing in Plasma at Steady-State
Timeframe: Intensive pharmacokinetic sampling: at designated timepoints up to 12 hours postdose
Cmax of DOR Following Twice-Daily Dosing in Plasma at Steady-State
Timeframe: Intensive pharmacokinetic sampling: at designated timepoints up to 12 hours postdose
Concentration at 12 Hours (C12) of DOR Following Twice-Daily Dosing in Plasma at Steady-State
Timeframe: Intensive pharmacokinetic sampling: at designated timepoints up to 12 hours postdose
Tmax of DOR Following Twice-Daily Dosing in Plasma at Steady-State
Timeframe: Intensive pharmacokinetic sampling: at designated timepoints up to 12 hours postdose
Percentage of Participants With ≥1 Adverse Event (AE)
Timeframe: Up to 24 weeks
Percentage of Participants With a Grade 3 or 4 AE
Timeframe: Up to 24 weeks
Percentage of Participants With Events of Death
Timeframe: Up to 24 weeks
Percentage of Participants Discontinuing From Study Intervention Due to an AE
Timeframe: Up to 24 weeks
Percentage of Participants Discontinuing From Study Intervention Due to a Drug-Related AE
Timeframe: Up to 24 weeks