Prevention of Oral DNA Damage by Black Raspberries

Inclusion Criteria: * Age 21-75 * Smoke 5 cigarettes per day or more for at least the past 12 months * Have an expired air carbon monoxide measurement of greater than 6 parts per million * No serious quit attempt in the last one month and not planning to quit in the next 4 months * Willing and able to attend all study visits * Able to read and write in English * Able to understand and provide consent to the study procedures * Willingness and ability to attend regular visits over a 14-week period and to respond to research contacts between the 5 Exclusion Criteria: * Unstable or significant medical conditions that affect participant safety or biomarker data in the past 3 months (e.g. recent heart attack, asthma or COPD) * Women currently pregnant or nursing * Use of any non-cigarette nicotine delivery product in the past 7 days (e.g. e-cigarettes, pipe or cigar) * Uncontrolled mental illness or inpatient treatment in the past 6 months; current suicide risk on clinical assessment * Any known allergy to raspberries * Use of marijuana or other illegal drugs daily or weekly in the past 3 months * Use of high dose antioxidant supplements in the past month * Use of antibiotics * Heavy drinking (\>4 drinks/day, 5 days/week) * Made no serious cigarette smoking quit attempt or have used any FDA-approved smoking cessation medication in the prior 30 days * No plan to quit smoking within the next 4 months