Endometrial Preparation by Short Course of Letrozole Before Hysteroscopic Removal of Endocavitary… (NCT04364581) | Clinical Trial Compass
UnknownPhase 4
Endometrial Preparation by Short Course of Letrozole Before Hysteroscopic Removal of Endocavitary Lesions
Egypt30 participantsStarted 2020-05-01
Plain-language summary
The aim of this study is to evaluate the effectiveness of short course of letrozole for endometrial preparation before hysteroscopic surgery for intracavitary lesions.
Who can participate
Age range18 Years – 45 Years
SexFEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with endouterine pathologies, identified by office diagnostic hysteroscopy during the early endometrial proliferative phase (cycle days 7 to 8)
Exclusion Criteria:
* Presence of large submucous (type I, type II) or endocavitary (type 0) fibroids (according to the European Society of Hysteroscopy Classification of Submucous Fibroids) with a diameter exceeding 4 cm, for which preoperative treatment with GnRH agonists is indicated.
* Hormonal therapies in the previous 8 weeks (including the drug of the study).
* Uterine and/or concomitant adnexal pathologies (including malignancy) for which hysteroscopic surgery was not considered either safe or the method to resolve the problem.
* Cardiovascular, hepatic, or renal impairment.
* Allergy to letrozole.
What they're measuring
1
Operative time
Timeframe: Until 2 hours from the start of operation