Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser

Inclusion Criteria: * Patient must have a hypertrophic burn scar treated by skin grafts or allowed to heal secondarily * Burn must have occurred within the last 2 years from time of recruitment * Patient must have symptoms of pain and/or itch and/or hypersensitivity in the hypertrophic burn scar area * Patient must already be planning to undergo laser treatment for their burn scar * Patient must be willing to undergo biopsy procedures * Patient must be willing and able to participate in the study with a year of follow-up * Not be pregnant or planning to become pregnant during the treatment phase of the study Exclusion Criteria: * Medical Conditions that preclude laser treatment * Active tanning, including the use of tanning booths, during the course of the study * Inability to complete surveys * Previous laser (PDL, CO2), surgical reconstructive treatment procedures done on the hypertrophic burn scar * Current treatment with other procedures or drugs (experimental or other) in area of interest * Medications that interfere with wound healing (oral steroids, immunosuppressive medications, chemotherapy or other) * Medication for itch (steroids, antihistamines, or other) * Medication for pain (opioids, topical pain treatment, gabapentin, ondasetron, paroxetine or other) * Adverse reactions to topical or local anesthetic agents needed for this study, if no alternative to the said agent exists * The study area should not be part of a contracture or other hypertrophic scar that w…