Capnography Monitoring in Ventilated Children

Inclusion Criteria: * Children on pressure controlled mechanical invasive or non-invasive ventilation on the Paediatric Intensive Care Unit of the University Children's Hospital Zurich * Newborns with a birthweight of at least 2.0 kg * Newborns with an age of at least 1 hour (age \> 60 minutes) * Children up to the last day of the 13th year of living * Ability of care taker or patient to understand verbal and written instructions and the general consent or informed consent in German or English * Obtained written general or informed consent as documented by signature * Available arterial line, i.e. a specific catheter inserted in an artery Exclusion Criteria: * Care taker or participant unable for linguistic, mental or other reasons or unwilling to understand verbal or written information and to give written informed consent in German or English * Care taker not available * Newborns with a birthweight below 2.0 kg * Newborns younger than 1 hour (age \<60 minutes) * Children with an age of 14 years onwards * Missing arterial line * Patients dependent on any other kind of respiratory support that is not compatible with the PcCO2-sensor or where a high leakage in the respiratory circuit makes PcCO2 measurements impossible (nasal mask ventilation, low-flow-/high-flow-ventilation, rebreathing mask, high- frequency-oscillation) * Patients where the investigators act on the assumption that mechanical ventilation will be discontinued and/or the arterial line will be removed within …