Fast Troponin as a Biomarker to Assess Exercise-induced Muscle Damage in Muscle Diseases (NCT04349566) | Clinical Trial Compass
CompletedNot Applicable
Fast Troponin as a Biomarker to Assess Exercise-induced Muscle Damage in Muscle Diseases
Denmark36 participantsStarted 2020-06-01
Plain-language summary
The purpose of the study is to explore the biomarker Fast Troponins response to exercise in patients with Becker muscular dystrophy, Limb-girdle muscular dystrophy and McArdle disease
Who can participate
Age range18 Years – 50 Years
SexALL
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Inclusion Criteria:
* The ability to cycle
* No concurrent medical condition that could interfere with interpretation of the results
* Molecular diagnosis of the specific condition in specified patient groups or healthy control
* No active muscle injury on the test day (caused by recent exercise, seizures, trauma, etc.)
Exclusion Criteria:
* Competing conditions at risk of compromising the results of the study
* Cardiac or pulmonary disease contraindicating peak exercise testing or strenuous exercise
* Veins that are too difficult to puncture for blood sampling, evaluated by the investigator
* Severe muscle weakness, that prevents the subject completing the exercise test, evaluated by the investigator