Inhaled Methoxyflurane for Pain Management in Nasal Bone Fracture Reduction

Inclusion Criteria: * Being a man or a woman between 18 and 75 years old, inclusively ; and * Being covered by the Quebec medical insurance (RAMQ); and * Presenting an uncomplicated nasal fracture requiring a delayed (7 to 10 days) closed reduction. Exclusion Criteria: * Pregnant or breastfeeding woman; or * Known for renal insufficiency (DFG \< 50) ; or * Known for hepatic impairment; or * Personal or familial allergies/hypersensitivity to fluorinated products; or * Contraindications to local anesthesia (including allergies); or * Personal or family history of malignant hyperthermia; or * Other facial fractures and/or significant injuries; or * Altered state of consciousness (dementia, drug intoxication, head trauma or other similar psychologic disorder); or * Significant respiratory impairment; or * Haemodynamic instability; or * Simultaneous use of alcohol, isoniazid, phenobarbital, rifampin, opioids, sedatives, hypnotics, sedative antihistaminics, general anesthetics, phenothiazines, tranquilizers, myorelaxants, nephrotoxic antibiotics (tetracycline, gentamicin, colistine, polymyxin B, amphotericin B); or * Use of cannabis or other illicit drugs the day of the procedure; or * Use of pain medication in past 6 hours; or * Use of Methoxyflurane : more than 6 mL in the last 48 hours or more than 15 mL in the last week or usage in the last 3 months; or * Need of sedation or general anesthesia for the procedure.