Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease

Inclusion Criteria: * Adults, aged 60 and over * Social security coverage * Signed informed consent * For patient with Chronic Kidney Disease, estimated glomerular filtration rate (eGFR) less than 45ml/min/1.73m2 (Stage 3b) for at least 3 months * For patient with Chronic Kidney Disease, stable clinical condition (i.e., Creatinine increased by a maximum of 25% in the previous 3 months) * For control group, 1:1 recruitment with case matching with CDK patients on gender (i.e., male and female) and the presence of diabètes (i.e., presence and absence) * For control group, blood test with control of renal function available and dated less than 6 months: with eGFR \> 60ml/min/1.73m2 (and control of glucose or glycated hemoglobin for diabetic controls) Exclusion Criteria: * Pregnant women * Under guardianship or minor * Neuromuscular disease * Dementia * Upper limbs history of surgery or pathologies preventing from fitting EMG electrodes or measuring handgrip force * Life expectancy of less than 3 months estimated by medical judgment * Programed hospitalization in the previous 3 months * Participation to another interventional clinical trial * Acute kidney disease * On dialysis or expected start of dialysis within next 3 months