WithdrawnNot Applicable

Intraoperative Navigation for Surgically Precise Resection of the Chest (INSPIRE)

Stopped: Research OR availibililty issues

Canada0Started 2025-11-01

Plain-language summary

While undergoing chest wall resection, a surgeon's major concern is obtaining an appropriate surgical margin. Difficulty or failure to do so can result in prolonged operative time, need for re-operation due to a positive resection margin, or need for complex chest wall reconstruction due to unnecessarily wide resection. Over the last decades, surgical navigation systems have been developed to improve operative precision in various surgical fields. This is achieved by integrating patient images with intraoperative findings.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Ability to provide informed consent
✓. Scheduled to undergo surgical resection of a chest wall lesion
✓. At least 18 years of age
✓. Must sign and be given a copy of the written informed consent form

Exclusion criteria

✕. Unresectable lesions or unstable patient condition, for which surgery is not recommended
✕. Participants with metallic implantation, such as ribs fixations, a pacemaker, or pedicle screws, which may affect the accuracy of CBCT
✕. Excluded at the discretion of the clinical investigator/surgeon, if they are enrolled in other studies that will result in combined radiation exposure exceeding standard of care
✕. Pregnant, lactating, or planning to become pregnant during the period of the evaluation

What they're measuring

Performance metrics for navigation-assisted chest wall resection

Timeframe: 2 years

Trial details

NCT IDNCT04328584

SponsorUniversity Health Network, Toronto

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-31

View on ClinicalTrials.gov More Thoracic Wall trials