Cesarean delivery is one of the most common major abdominal operation in women worldwide. The incidence of postpartum infection has been estimated to be 1-4% after vaginal delivery and 10-20% after Cesarean delivery. Although it is widely performed, manual removal of the placenta is still a conflicting issue due to the risk of post-partum endometritis. All cesarean patients are randomized according to the removal of placenta from the uterus after childbirth; manually (Group 1) or controlled cord traction without putting fingers inside the uterus (Group 2). The aim of this study is to examine whether there is an association between the method of removal of the placenta and postpartum white blood cell increase in nonanemic, singleton, low-risk group of women with term pregnancies, who underwent elective cesarean delivery under general anesthesia.
Who can participate
Age range
18 Years – 45 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Nonanemic pregnancies
* Singleton pregnancies
* Term pregnancies
* Elective cesarean sections
Exclusion Criteria:
* Patients having umbilical cord prolapse,
* Patients having placenta previa
* Patients having preterm rupture of mebranes
* Patients having maternal infection
* Patients having multiple gestation
* Patients having antepartum hemorrhage
* Patients having severe pre-eclampsia
* Patients having placenta previa
* Patients having placental abruption
* Patients having uncontrolled gestational diabetes
* Heart disease
* Liver disorders
* Renal disorders
* Coagulopathy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from Baseline Leukocyte Level at Postpartum Day 1
Timeframe: Before delivery and postpartum day 1
2
Detection of Leukocyte Count
Timeframe: Postpartum day 2
3
Detection of Number of Patients with Fever
Timeframe: On postpartum day 1
4
Detection of Number of Patients with Fever
Timeframe: On postpartum day 2
5
Number of Participants with Postpartum Endometritis
Timeframe: Postpartum day 10
Trial details
NCT IDNCT04323241
SponsorHaydarpasa Numune Training and Research Hospital