A Histological Study Evaluating Silk Voice and Crosslinked Hyaluronic Acid

Inclusion Criteria: * To be eligible for enrollment, the Subject must meet the following: * males or non-pregnant, non-breastfeeding females 21 to 65 years old who are willing to comply with the requirements of the study, including sequential photography, periodic check-ins and retrieval of implanted materials; * women of childbearing potential using an acceptable form of birth control during the study period and willingness to take a urine pregnancy test at baseline and at the biopsy date; * sign the Informed Consent form and the Authorization for Use and Release HIPAA form prior to any study-related procedures being performed. * read and understand English Exclusion Criteria: * Patients will not enroll in the study if they meet any of the following exclusion criteria: * a history of allergy or hypersensitivity to injectable hyaluronic acid gel; * a history of allergy or hypersensitivity to silk; * a history of severe allergies manifested by a history of anaphylaxis or history or presence of multiple severe allergies * history of allergies of lidocaine * a history of susceptibility to keloid formation, hypertrophic scarring, and pigmentation disorders. * currently have a hyaluronic acid device implanted * the presence of any contraindication to the implant procedures, including use of platelet inhibiting agents or other anticoagulant, in a relevant period before study entry (per the treating investigator's judgment); * the presence of any conditi…