This study will examine the effects of doses of opioid/placebo and doses of sedative/placebo, alone and in combination. The primary outcomes are related to pharmacodynamic measures (subjective ratings of drug liking and other abuse-related effects; physiological outcomes) to determine the interaction effects of these compounds.
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Change in Subject-Rated Outcome: Visual Analog Scale (VAS) Drug Liking
Timeframe: This outcome was recorded prior to and in regular intervals after drug administration for the duration of the session (approx. 8 hours per session).