Stopped: Slow enrollment and difficulty getting patients to complete the study visits (significantly impacted by COVID-19 pandemic)
The goal of this research is to determine if the Tangible Boost system adequately replenishes the Hydra-PEG coating on the surface of a rigid contact lens. Hydra-PEG is a coating for soft and rigid contact lens, primarily composed of polyethylene glycol-based hydrogel, which is covalently bound to the surface of a contact lens. The Hydra-PEG coating is intended to improve wettability and comfort with contact lenses and is currently FDA approved on a number of contact lenses. For patients with Stevens Johnson Syndrome (SJS) (SS), or Graft versus Host disease (GVHD), diminished efficacy of the Hydra-PEG coating can lead to significant decline in satisfaction with the lenses over time. This is a prospective study to evaluate the efficacy of Tangible Boost, a monthly conditioning solution, to replenish the Hydra-PEG coating on rigid gas permeable contact lenses for patients with SJS, GVHD, and SS. Outcomes from this patient population will be compared to patients with dry eye disease.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Visual Acuity
Timeframe: 3 months
Visual Acuity
Timeframe: 6 months
Contact Lens Comfort
Timeframe: 3 months
Contact Lens Comfort
Timeframe: 6 months
Ocular Surface Staining
Timeframe: 3 months
Ocular Surface Staining
Timeframe: 6 months
Tear break up time
Timeframe: 3 months
Tear break up time
Timeframe: 6 months