Active — Not RecruitingNot Applicable

Transcranial Direct Current to Treat Epilepsy at Home

United States4 participantsStarted 2021-05-26

Plain-language summary

This is a placebo-controlled study of feasibility and potential effectiveness of transcranial direct current stimulation (tDCS) in the home environment to reduce seizures and EEG spikes.

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18-100, inclusive. * Has a clinical diagnosis of epilepsy * Has at least 4 countable seizures per month * Has not had control with at least 2 anti-seizure medicines * Able to maintain a constant medication for duration of the study (rescue meds allowed) * Subject or legally authorized representative is able to understand consent and keep a seizure diary in English Exclusion Criteria: * A disease likely to progress over course of the study * Psychogenic non-epileptic seizures * Suicide attempt or psychiatric hospitalization past 2 years * A skin condition interfering with scalp electrodes or allergy to silver * Women will verify not pregnant, and if applicable, have a serum pregnancy test

What they're measuring

Change in seizures per month

Timeframe: Within 1 week of end of the SHORT treatment and within 1 week of end of the LONG treatment

Change in seizures per month

Timeframe: Recorded at time of study entry (BASELINE) and within 1 week of end of the SHORT treatment

Change in seizures per month

Timeframe: Recorded at time of study entry (BASELINE) and within 1 week of end of the LONG treatment

Trial details

NCT IDNCT04309812

SponsorStanford University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

View on ClinicalTrials.gov More Epilepsies, Partial trials