CompletedNot Applicable

An Innovative Conversational Agent (Quitbot) for Smoking Cessation

United States1,647 participantsStarted 2022-07-24

Plain-language summary

This phase III trial compares two remote digital smoking cessation programs to see how well they work for quitting smoking.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 or older * Smokes at least one cigarette a day for the past 12 months * Wants to quit cigarette smoking within the next 30 days (consistent with text messaging intervention trials) * If concurrently using any other nicotine or tobacco products, wants to quit using them within the next 30 days * Interested in learning skills to quit smoking * Willing to be randomly assigned to either intervention * Resides in United States (US) and will continue to reside in the US for the next 12 months * Has at least daily access to their own smartphone * Has text messaging on their smartphone and knows how to download a smartphone application * Willing and able to read in English, and * Not using other smoking cessation interventions (This eligibility requirement helps ensure results are due to the treatments we recommend rather than those that participants are doing on their own.) Exclusion Criteria: * The reverse of the inclusion criteria

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Number of Participants With 30-day Cigarette Smoking Cessation

Timeframe: At 12 months after randomization

Trial details

NCT IDNCT04308759

SponsorFred Hutchinson Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-01

Results submitted2026-03-19

View on ClinicalTrials.gov More Smoking &Amp; Tobacco Cessation trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.