CompletedNot Applicable

Thrombotic Complications After Central Venous Catheterization

Netherlands173 participantsStarted 2019-12-01

Plain-language summary

Rationale: Complications related to central venous catheterization are mechanical, infectious or thrombotic in origin. Potential complications of catheter-related thrombosis are not insubstantial and include pulmonary embolism, post-thrombotic syndrome or thrombophlebitis. Prevalence and incidence of catheter-related thrombosis at the intensive care unit is unclear and treatment, especially of asymptomatic thrombosis, remains ambiguous. Therefore a study is warranted that evaluates the prevalence and incidence of catheter-related thrombosis and investigates its potential consequences. We hypothesize that the incidence of catheter-related thrombosis is 5-15%. Objective: To assess the prevalence and incidence of symptomatic and asymptomatic catheter-related thrombosis.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Central venous cannulation of the internal jugular vein, subclavian vein, or femoral vein * ≥ 48 hours catheter indwelling time Exclusion Criteria: * Removal of the CVC within 48 hours after placement * Pre-existent thrombosis at vein of insertion site * Discharge of patients from ICU with CVC in situ * Inability to perform compression and colour Doppler ultrasound evaluation of cannulated vein

What they're measuring

Incidence and prevalence of catheter-related thrombosis

Timeframe: Date of central venous catheter insertion until date of catheter removal, assessed up to 28 days after CVC insertion

Trial details

NCT IDNCT04302376

SponsorAmsterdam UMC, location VUmc

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-02-01

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